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Writer's pictureVicki Hexter

Polynucleotides: The Revolutionary Ingredient Transforming Skincare


PDRN Professional Product
PDRN Professional Microneedling Product

Polynucleotides: The Revolutionary Ingredient Transforming Skincare

In the ever-evolving world of skincare, innovative ingredients continue to push the boundaries of what's possible in skin rejuvenation. One such groundbreaking component that has been gaining significant attention is polynucleotides - a powerful molecule that's changing the landscape of aesthetic treatments and at-home skincare routines.


Understanding Polynucleotides

Polynucleotides are long chains of nucleotides, the fundamental building blocks of DNA and RNA. In the context of skincare, these molecules have emerged as a game-changing ingredient with remarkable regenerative and healing properties. Unlike traditional skincare components, polynucleotides work at a cellular level, offering a more profound approach to skin repair and rejuvenation.


Polydeoxyribonucleotide (PDRN): A Specific Type of Polynucleotide

While polynucleotides encompass a broad category of molecules, Polydeoxyribonucleotide (PDRN) is a specific type that has garnered significant attention in both medical and cosmetic fields. Derived typically from salmon DNA, PDRN has shown exceptional capabilities in tissue regeneration, wound healing, and skin revitalisation.


The Science Behind Polynucleotides in Skincare

Polynucleotides work through several key mechanisms:

  • Cellular Regeneration: They stimulate fibroblast activity, encouraging the production of collagen and elastin.

  • Wound Healing: PDRN has been shown to accelerate tissue repair and reduce inflammation.

  • Hydration: These molecules help improve skin's moisture retention and overall hydration.

  • Anti-Aging: By promoting cellular renewal, polynucleotides can help reduce the appearance of fine lines and improve skin texture.


Juliette Armand's Advanced Polynucleotide Solutions

Juliette Armand has been at the forefront of incorporating polynucleotide technology into professional and home skincare treatments. Their comprehensive PDRN product line demonstrates a sophisticated approach to skin rejuvenation:


Juliette Armand Ameson PDRN Range
Juliette Armand Ameson PDRN Range

Professional Treatment: Ameson PDRN 2%


PDRN Professional Microneedling Product
PDRN Professional Product

The Ameson PDRN 2% is a professional microneedling product that delivers a concentrated dose of polynucleotides directly into the skin. This treatment is designed to:

  • Enhance skin regeneration

  • Improve skin texture and tone

  • Stimulate natural healing processes

  • Provide intensive repair for damaged or aging skin.



Home Care Product Line

Juliette Armand offers a complete home care range to complement their professional treatments:

PDRN Rejuvenation Serum
PDRN Rejuvenation Serum

PDRN Rejuvenation Serum

A lightweight, potent formulation that delivers polynucleotides directly to the skin. Ideal for daily use, this serum helps:

- Boost skin's natural repair mechanisms

- Provide deep hydration

- Improve overall skin elasticity


PDRN Rejuvenation Serum Ingredients
PDRN Rejuvenation Serum Ingredients

The action mechanism of PDRN Rejuvenation Serum is based on:

  1. The multifaceted action mechanism of PDRN polynucleotide in a biological and mechanical way. 

  2. The synergy of PDRN with the targeted active ingredients to enhance and improve basic vital functions of the skin and its physiology: 

  3. Peptides: Copper Tripeptide, Oligopeptide-51, Peptilift 

  4. Vitamins: B-complex Vitamins (B3, B5, B12), stabilized Vitamin C (AA2G) 

  5. Low and medium molecular weight Hyaluronic acid (LMW & MMW) 

  6. Specialised complex of moisturising ingredients. 


PDRN Rejuvenation Cream
PDRN Rejuvenation Cream

PDRN Rejuvenation Cream

A rich, nourishing cream that continues the work of the serum. Benefits include:

- Long-lasting hydration

- Supporting skin's barrier function

- Reducing the appearance of fine lines and wrinkles.


PDRN Rejuvenation Cream Ingredients
PDRN Rejuvenation Cream Ingredients

The action mechanism of PDRN Rejuvenation Cream is based on:

  1. The multifaceted mechanism of action of PDRN polynucleotide

  2. The synergy of PDRN with the below targeted active ingredients to enhance and improve basic vital functions of the skin and its physiology:

  3. Peptides: Copper Tripeptide, Peptilift, Oligopeptide-51

  4. Medium molecular weight Hyaluronic acid (MMW)

  5. Ceramides and moisture retention agents

  6. Vitamins: Vitamin B3 (Niacinamide), Vitamin E (Tocopherol).







PDRN Rejuvenation Microneedling

PDRN Rejuvenation Microneedling
PDRN Rejuvenation Microneedling

A home-use microneedling solution that allows individuals to experience professional-grade treatment in the comfort of their own space. This product:

- Enhances product absorption

- Stimulates collagen production

- Provides a non-invasive method of skin rejuvenation

PDRN Microneedling device Ingredients
PDRN Microneedling device Ingredients

The action mechanism of PDRN Rejuvenation Microneedling is based on: 

  1. In the multifaceted action mechanism of PDRN polynucleotide in a biological and mechanical way. 

  2. The synergy of the regenerative and repairing action of PDRN with self-microneedling technology for stimulation of the natural mechanisms of skin cell renewal and collagen production, as well as simultaneous direct and faster penetration of polynucleotide and other serum’s active ingredients. 

  3. The synergy of PDRN with the targeted active ingredients to enhance and improve basic vital functions of the skin and its physiology:  

  4. Peptides: Copper Tripeptide, Argireline 

  5. Medium molecular weight Hyaluronic acid (MMW) 

  6. Vitamins: B-complex Vitamins (B3, B5, B12), stabilized Vitamin C (AA2G) 

  7. Specialized complex of moisturizing ingredients, Centella Asiatica 


Key Differences: Polynucleotides vs. Traditional Skincare Ingredients

Unlike many traditional skincare ingredients that work superficially, polynucleotides:

- Penetrate deeper into the skin

- Provide more comprehensive cellular-level regeneration

- Offer longer-lasting results

- Have minimal irritation potential


Who Can Benefit?

Polynucleotide treatments are suitable for:

- Individuals showing signs of aging

- Those with uneven skin texture

- People looking to improve overall skin health

- Individuals with sensitive or reactive skin


The Future of Skincare

As research continues, polynucleotides are proving to be more than just a passing trend. They represent a significant advancement in understanding and supporting skin health at a cellular level.


Juliette Armand's commitment to incorporating PDRN technology demonstrates the brand's forward-thinking approach to skincare, offering both professional and home care solutions that harness the power of polynucleotides.


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